Psychedelic Treatments in Healthcare

  • problem statement / what is driving the trend

    • desire to have actually impactful solutions to treat issues rather than ones that don't actually work like anti depressants.

    • treat the root of the issue not the symptoms

  • drugs of topic

    • MDMA

    • ketamin

    • psilocybin

  • applications

    • PTSD

    • depression & anxiety

    • OCD

    • headaches & migraines

    • other mental health

    • inflammatory issues

  • ketamine clinics are on the rise (MDMA too)

    • 400+ in the US

    • $200mm+ raised over last 2 years to open more

  • headwinds

    • FDA approval / IP

      • not yet

      • will increase molecular offerings

    • long timeline to commercialization

    • bad hype / risk for substance abuse or even worse consequences

      • don't wanna see what happened to crypto happen here because this includes real drugs and health

  • tailwinds

    • social landscape

    • COVID-19

    • regulatory landscape

    • increasing focus on mental health

    • big pharma becoming interested

    • data being released that existing solutions are not working

      • new federal analysis released that long term use of anti depressants is rising yet very little is known about their long term benefits

        • does improve depression symptoms over the first few months

  • funds in the space

    • PsyMed Ventures

    • Noetic Fund

    • Lightbank? and other more generalist

    • Neo Kuma

    • Vine Ventures

    • Palo Santo

  • questions & thoughts

    • venture backable?

      • deep tech usually have longer than venture investing timelines with large upfront capital requirement and potentially fast exits to another large pharma or IPO

      • precedents: Jazz Pharma buying GW Pharma for 7.2bn, Pfizer buying Arena Pharma for 6.7bn. Both for cannabinoid applications

      • timeline closer to 2030

    • what needs to come first is cannabis based products?

    • perhaps combine w mental health solutions since those are taking off

    • biggest strides will be in actual drug development. distribution and accessibility will follow always.

    • focus on team w a strong technical background and GTM background in biotech

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